Supplemental Data

Supplemental Data for Pathak et al., Neuron 56, pp. 124-140

Document S1. Supplemental Results, Experimental Procedures, Figures, and Tables

Movie S1.
View of the conformational changes between the Kv1.2 models of the resting and open states from the side of the membrane. Only a single VSD is shown attached to the tetramer of the PD for clarity. The models are represented as in FigureĀ 7A. All movies were made by Laura Lynn Gonzalez ().
Movie S2.
View of the conformational changes between the Kv1.2 models shown in Movie S1 from the extracellular side of the membrane.
Movie S3.
View of the conformational changes between the Kv1.2 models shown in Movie S1 from the intracellular side of the membrane.
Model 1.
Open (activated) state model of the Kv1.2 channel generated as described in Experimental Procedures.
Model 2.
Closed (resting) state model of the Kv1.2 channel generated as described in Experimental Procedures.